مدل‌سازی حذف آنتی بیوتیک اکسی تتراسایکلین با استفاده از نانولوله‌های کربنی عامل‌دار شده با گروه آمین؛ استفاده از روش سطح پاسخ

نوع مقاله : مقاله پژوهشی

نویسنده

گروه علوم و مهندسی محیط زیست، دانشکده کشاورزی و محیط زیست، دانشگاه اراک، ایران

چکیده

حضور ترکیبات دارویی در محیط‌زیست تهدیدی جدی برای بشر تلقی می ­شود و ورود این مواد به منابع آبی، سبب آلودگی گیاهان، خاک و جانوران شده و مشکلاتی را برای بهداشت عمومی ایجاد می­ کند، این امر تأمین تسهیلات تصفیة فاضلاب در منابع تولید این مواد را ضروری می ­نماید تا از رها شدن بی­ رویة آن­ها در محیط‌زیست جلوگیری به‌عمل آید. از این ­رو، استفاده از نانو جاذب ­ها، روشی نوین با کارایی بالا جهت حذف آنتی­ بیوتیک ­ها از محیط­ های آبی است. نانولوله ­کربنی به‌دلیل خاصیت منحصر به فرد خود، از جمله موادی است که می­ توان جهت حذف آنتی ­بیوتیک ­ها از آن استفاده کرد. در این مطالعه، نانو جاذب از نانولوله­ های ­کربنی تهیه شده و سپس به روش حلال گرمایی، مغناطیسی شد و با گروه آمین اتیلن ­دی­ آمین عامل ­دار گردید. آنالیز­های وزن‌سنجی حرارتی، عنصری، طیف‌سنجی مادون قرمز تبدیل فوریه و آنالیز تعیین قدرت مغناطیسی به‌منظور تشخیص و بررسی ویژگی­ های نانوجاذب سنتز شده صورت پذیرفت. سپس این نانوکامپوزیت برای حذف آنتی‌بیوتیک­ اکسی تتراسایکلین از محلول­ های آبی در سیستم ناپیوسته مورد مطالعه قرار گرفت. عوامل مؤثر بر میزان جذب مانند pH، مقدار جاذب، زمان تماس و غلظت اولیة آنتی ­بیوتیک­ مورد بررسی قرار گرفت. نتایج نشان داد بیشترین ظرفیت جذب تعادلی برای آنتی ­بیوتیک­ مورد مطالعه 122/8 میلی ­گرم بر گرم است. همچنین نانوجاذب سنتز شده در این تحقیق از ظرفیت جذب نسبتاً بالایی برای جذب آنتی­ بیوتیک­ اکسی تتراسایکلین برخوردار و استفاده از این جاذب در سیستم تصفیة پساب از نظر محیط­زیستی توجیه ­پذیر می­ باشد.

کلیدواژه‌ها

عنوان مقاله [English]

Modeling the removal of the Oxytetracycline antibiotic using Amine-functionalized multi-walled carbon nanotubes; Use of the response surface methodology

نویسنده [English]

  • Ali Kazemi

Department of Environmental Science and Engineering, Faculty of Agriculture and Environment, Arak University, Arak, Iran

چکیده [English]

The presence of drug compounds in the environment is considered to be a serious threat to mankind and the entry of these substances into water resources leads to contamination of plants, soil and animals and creates problems for public health, which provides sewage treatment facilities in production resources It makes this material necessary to prevent them from releasing them in the environment. Hence, the use of nano-adsorbents is a novel high-performance method for removing antibiotics from aqueous media. Because of its unique properties, Multi-walled carbon nanotube (MWCNT) is one of the substances that can be used to remove antibiotics. In this study, MWCNT was synthesized and then became magnetic by magnetic thermal solvent method and was functionalized with the ethylenediamine amine group. The synthesized nanocomposite was characterized by Fourier Transform Infrared spectroscopy, vibrating sample magnetometry, thermal gravimetric analysis and CHNS elemental analysis. The nanocomposite was used for removal of Oxytetracycline (OTC) antibiotic from aqueous solution in batch system. The effect of various factors, such as pH, dosage of Magnetic MWCNT, contact time and initial concentration of antibiotic were investigated. The maximum equilibrium adsorption capacity for Oxytetracycline removal was 122.8 mg/g. The results showed that the synthesized nanocomposite in this research has a relatively high adsorption capacity for Oxytetracycline adsorption and the application of this adsorbent in wastewater treatment system could be reasonable in terms of the economic aspect. 

کلیدواژه‌ها [English]

  • Antibiotic removal
  • Oxytetracycline
  • magnetic multi-walled carbon nanotube
Allen, H.K., Donato, J., Wang, H.H., Cloud-Hansen, K.A., Davies, J., Handelsman, J., 2010. Call of the wild: antibiotic resistance genes in natural environments. Nature Reviews Microbiology 8(4), 251-259.
Azizi, K., Karimi, M., Nikbakht, F., Heydari, A., 2014. Direct oxidative amidation of benzyl alcohols using EDTA@ Cu (II) functionalized superparamagnetic nanoparticles. Applied Catalysis A: General 482, 336-343.
Barka, N., Abdennouri, M., Makhfouk, M.E., 2011. Removal of Methylene Blue and Eriochrome Black T from aqueous solutions by biosorption on Scolymus hispanicus L.: Kinetics, equilibrium and thermodynamics. Journal of the Taiwan Institute of Chemical Engineers 42(2), 320-326.
Baziar, M., Azari, A., Karimaei, M., Gupta, V.K., Agarwal, S., Sharafi, K., Maroosi, M., Shariatifar, N., Dobaradaran, S., 2017. MWCNT-Fe3O4 as a superior adsorbent for microcystins LR removal: Investigation on the magnetic adsorption separation, artificial neural network modeling, and genetic algorithm optimization. Journal of Molecular Liquids 241, 102-113.
Bound, J.P., Voulvoulis, N., 2004. Pharmaceuticals in the aquatic environment-a comparison of risk assessment strategies. Chemosphere 56(11), 1143-1155.
Cui, L., Wang, Y., Gao, L., Hu, L., Yan, L., Wei, Q., Du, B., 2015. EDTA functionalized magnetic graphene oxide for removal of Pb (II), Hg (II) and Cu (II) in water treatment: Adsorption mechanism and separation property. Chemical Engeering Journal 281, 1-10.
Fan, L., Luo, C., Li, X., Lu, F., Qiu, H., Sun, M., 2012. Fabrication of novel magnetic chitosan grafted with graphene oxide to enhance adsorption properties for methyl blue. Journal of Hazardous Materials 215-216, 272-279.
Fatta-Kassinos, D., Meric, S. and Nikolaou, A., 2011. Pharmaceutical residues in environmental waters and wastewater: current state of knowledge and future research. Analytical and Bioanalytical Chemistry 399(1), 251-275.
Ghasemi, E., Heydari, A., Sillanpää, M., 2017. Superparamagnetic Fe3O4@EDTA nanoparticles as an efficient adsorbent for simultaneous removal of Ag(I), Hg(II), Mn(II), Zn(II), Pb(II) and Cd(II) from water and soil environmental samples. Microchemical Journal 131, 51-56.
Harja, M., Ciobanu, G., 2017. Removal of oxytetracycline from aqueous solutions by hydroxyapatite as a low-cost adsorbent. In E3S Web of Conferences, (Vol. 22, p. 00062). EDP Sciences.
Harja, M., Ciobanu, G., 2018. Studies on adsorption of oxytetracycline from aqueous solutions onto hydroxyapatite. Science of the Total Environment 628, 36-43.
Hu, X.J., Liu, Y.G., Wang, H., Chen, A.W., Zeng, G.M., Liu, S.M., Guo, Y.M., Hu, X., Li, T.T., Wang, Y.Q., Zhou, L., Liu, S.H., 2013. Removal of Cu(II) ions from aqueous solution using sulfonated magnetic graphene oxide composite. Separation and Purification Technology 108, 189-195.
Jones, A.D., Bruland, G.L., Agrawal, S.G., Vasudevan, D., 2005. Factors influencing the sorption of oxytetracycline to soils. Environmental Toxicology and Chemistry, 24, 761-770.
Jones, O.A.H., Voulvoulis, N. and Lester, J.N., 2002. Aquatic environmental assessment of the top 25 English prescription pharmaceuticals. Water Research 36(20), 5013-5022.
Kümmerer, K. and Henninger, A., 2003. Promoting resistance by the emission of antibiotics from hospitals and households into effluent. Clinical Microbiology and Infection 9(12), 1203-1214.
Kazemi, A., Bahramifar, N., Heydari, A. and Olsen, S.I., 2019. Synthesis and sustainable assessment of thiol-functionalization of magnetic graphene oxide and superparamagnetic Fe3O4@ SiO2 for Hg (II) removal from aqueous solution and petrochemical wastewater. Journal of the Taiwan Institute of Chemical Engineers 95,78-93.
ter Laak, T.L., Gebbink, W.A. and Tolls, J., 2006. The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. Environmental Toxicology and Chemistry: An International Journal 25(4), 904-911.
Li, L., Fan, L., Sun, M., Qiu, H., Li, X., Duan, H., Luo, C., 2013. Colloids and Surfaces B : Biointerfaces Adsorbent for chromium removal based on graphene oxide functionalized with magnetic cyclodextrin- chitosan. Colloids Surfaces B Biointerfaces 107, 76-83.
Mihciokur, H., Oguz, M., 2016. Removal of oxytetracycline and determining its biosorption properties on aerobic granular sludge. Environmental Toxicology and Pharmacology 46, 174-182.
Oleszczuk, P., Pan, B., Xing, B., 2009. Adsorption and desorption of oxytetracycline and carbamazepine by multiwalled carbon nanotubes. Environmental Science & Technology 43, 9167-9173.
Peer, F.E., Bahramifar, N., Younesi, H., 2018. Removal of Cd (II), Pb (II) and Cu (II) ions from aqueous solution by polyamidoamine dendrimer grafted magnetic graphene oxide nanosheets. Journal of the Taiwan Institute of Chemical Engineers 87, 225-240.
Santaeufemia, S., Torres, E., Mera, R. and Abalde, J., 2016. Bioremediation of oxytetracycline in seawater by living and dead biomass of the microalga Phaeodactylum tricornutum. Journal of Hazardous Materials 320, 315-325.
Shahbazi, A., Younesi, H., Badiei, A., 2013. Batch and fixed-bed column adsorption of Cu(II), Pb(II) and Cd(II) from aqueous solution onto functionalised SBA-15 mesoporous silica. The Canadian Journal of Chemical Engineering 91, 739-750.
Shen, J., Hu, Y., Shi, M., Li, N., Ma, H., Ye, M., 2010. One step synthesis of graphene oxide-magnetic nanoparticle composite. The Journal of Physical Chemistry 114, 1498-1503.
Song, Y., Sackey, E.A., Wang, H. and Wang, H., 2019. Adsorption of oxytetracycline on kaolinite. PLoS One 14(11), p.e0225335.
Wang, D., Liu, L., Jiang, X., Yu, J., Chen, X. and Chen, X., 2015. Adsorbent for p-phenylenediamine adsorption and removal based on graphene oxide functionalized with magnetic cyclodextrin. Applied Surface Science 329, pp.197-205.
Wang, D., Xu, H., Yang, S., Wang, W. and Wang, Y., 2018. Adsorption property and mechanism of oxytetracycline onto willow residues. International Journal of Environmental Research and Public Health 15(1), p.8.
Wang, Y., Liang, S., Chen, B., Guo, F., Yu, S., Tang, Y., 2013. Synergistic Removal of Pb(II), Cd(II) and Humic Acid by Fe3O4@Mesoporous Silica-Graphene Oxide Composites. PLoS One 8, 2–9.
Wu, H.X., Wu, J.W., Niu, Z.G., Shang, X.L. and Jin, J., 2013. In situ growth of monodispersed Fe3O4 nanoparticles on graphene for the removal of heavy metals and aromatic compounds. Water science and Technology 68(11), pp.2351-2358.
Yang, X., Zhang, X., Ma, Y., Huang, Y., Wang, Y., Chen, Y., 2009. Superparamagnetic graphene oxide–Fe3O4 nanoparticles hybrid for controlled targeted drug carriers. Journal of Materials Chemistry 19, 2710.
Zaher, A., Taha, M., Farghali, A.A., Mahmoud, R.K., 2020. Zn/Fe LDH as a clay-like adsorbent for the removal of oxytetracycline from water: combining experimental results and molecular simulations to understand the removal mechanism. Environmental Science and Pollution Research 27, 12256–12269.
Zhang, W., Shi, X., Zhang, Y., Gu, W., Li, B., Xian, Y., 2013. Synthesis of water-soluble magnetic graphene nanocomposites for recyclable removal of heavy metal ions. Journal of Materials Chemistry A 1, 1745.